Crashes after 2 min

Hey everybody,
I tried to search for this problem but didn't find a solution.
Installing the mod pack was quite a challenge because I messed up the modorganizer.ini.
After fixing my problem I started modorganizer and not a single mod was activatet. So I left clicked and let every mod activate.
Now to the problem: I can start skyrim through the MO and load g times are decent. But I can only play for about 2-3 minutes before crashing to the desktop without an error message.

Which mods should be activatet in MO and which should not?

Greetings,
Tschonaht