I've started a new game as a beggar in Riften. Besides the occasional CTD, the game has run perfectly fine. After returning to Riften, I went to the alchemy shop to turn in a quest. Whenever I entered, the game CTD'd on the loading screen. I tried to enter the Bee and Barb to see if it was an issue with just that house. However, it crashed there as well. Whenever I enter a building, my game CTD's on the loading screen.